About

My initial training was in cell biology and physiology, with a parallel formation in computer science. I moved to bioinformatics for my master’s, and it has been my field ever since. My PhD, at the Atelier de Bioinformatique in Paris, dealt with the comparison and alignment of protein structures — the object that has occupied me since.

Along the way I have worked on viral metagenomics, on the functional annotation of orphan genes, and on the physical modelling of proteins, each time because the previous question required it. Wanting to understand the sequence–structure relationship well enough to model it took me to Michael Levitt’s group at Stanford in 2007; wanting to add the evolutionary dimension took me to ISYEB in 2016, where the work on folds as phylogenetic characters became possible.

Positions

2026 – 2027	Délégation CNRS 50%, ISYEB
2026	Visiting researcher, University College of London University — Christine Orengo’s group
2025 – 2026	Délégation CNRS 100%, ISYEB
2016 –	Associate professor (SU), ABI Team -ISYEB UMR 7205
2010 – 2016	Associate professor (SU), Bibip Team - IMPMC UMR 7590
2007	Visiting researcher, Stanford University — Michael Levitt’s group
2006 – 2010	Associate professor (SU), Analytical Genomics Group - UMRS 511
2005 – 2006	Postdoctoral fellow (ATER Université Paris Diderot), Modelling in Integrative Biology Team - Institut Jacques Monod
2002 – 2005	PhD (UPMC), Atelier de Bioinformatique, UPMC — advisors J. Pothier and P. Netter

Degrees

Habilitation (HDR), Sorbonne Université, 2023 — Protein Structure and Evolution.

PhD, Université Pierre et Marie Curie, 2005 — Methods for detecting structural similarities: characterising conserved motifs in structure families for genome annotation.

MSc Genome Analysis and Molecular Modelling, Universités Paris 6 and 7, 2002.